Izigulana ze-COVID-19 Pneumonia Zibonisa Uphuculo Olubalulekileyo Emva Konyango lweLaser kwiSibhedlele iMassachusetts General

Inqaku elipapashwe kwi-American Journal of Case Reports libonisa amandla onyango lwe-photobiomodulation olusebenzayo kwizigulana ezine-COVID-19.
LOWELL, MA, Agasti 9, 2020 /PRNewswire/ — Umphandi oPhambili kunye nombhali oPhambili uGqr. Scott Sigman namhlanje uxele iziphumo ezilungileyo zokusetyenziswa kokuqala konyango lwelaser ukunyanga isigulana esine-pneumonia ye-COVID-19. Inqaku elipapashwe kwi-American Journal of Case Reports libonisa ukuba emva konyango oluxhasayo ngonyango lwe-photobiomodulation (PBMT), isalathisi sokuphefumla sesigulana, iziphumo ze-radiographic, imfuno yeoksijini, kunye nesiphumo ziphucukile kwiintsuku ezimbalwa ngaphandle kwesidingo somatshini womoya. 1 Izigulana ezibandakanyiweyo kule ngxelo zithathe inxaxheba kuvavanyo lweklinikhi olungacwangciswanga lwezigulana ezili-10 ezine-COVID-19 eqinisekisiweyo.
Isigulana, esineminyaka engama-57 ubudala saseMelika esifunyaniswe sine-SARS-CoV-2, sangeniswa kwigumbi lokhathalelo oluphezulu esine-respiratory distress syndrome kwaye sasidinga ioksijini. Safumana iiseshoni ezine ze-PBMT zemizuzu engama-28 yonke imihla sisebenzisa isixhobo sonyango lwelaser esivunyiweyo yi-FDA (i-ASA Laser, e-Itali). Ilaser yonyango lwe-MLS esetyenzisiweyo kolu phononongo isasazwa kuphela eMntla Melika yiCutting Edge Laser Technologies yaseRochester, NY. Impendulo yesigulana kwi-PBMT ihlolwe ngokuthelekisa izixhobo ezahlukeneyo zovavanyo ngaphambi nasemva konyango lwelaser, zonke ezo zinto zaphucuka emva konyango. Iziphumo zibonisa ukuba:
Ngaphambi konyango, isigulane sasilele ebhedini ngenxa yokukhohlela okukhulu kwaye sasingakwazi nokushukuma. Emva konyango, iimpawu zokukhohlela zesigulane zaphela, waza wakwazi ukuhla emhlabeni ngoncedo lwemithambo ye-physiotherapy. Ngosuku olulandelayo wakhutshwa kwiziko lokubuyisela impilo esempilweni encediswa yi-oxygen encinci. Emva kosuku olunye kuphela, isigulane sakwazi ukugqiba iimvavanyo ezimbini zokunyuka izitebhisi nge-physiotherapy saza sadluliselwa emoyeni wegumbi. Ekulandeleni, ukuchacha kwakhe kweklinikhi kwathatha iiveki ezintathu zizonke, ixesha eliphakathi lidla ngokuba ziiveki ezintandathu ukuya kwezisibhozo.
“Unyango olongezelelweyo lwe-photobiomodulation luye lwabonakala lusebenza kakuhle ekunyangeni iimpawu zokuphefumla kwiimeko ezinzima ze-pneumonia ezibangelwa yi-COVID-19. Sikholelwa ukuba olu khetho lonyango luyindlela efanelekileyo yokugcina,” utshilo uGqr. Sigman. “Kukho imfuneko eqhubekayo yezonyango yeendlela zonyango ezikhuselekileyo nezisebenzayo ze-COVID-19. Siyathemba ukuba le ngxelo kunye nezifundo ezilandelayo ziya kukhuthaza abanye ukuba baqwalasele iimvavanyo ezongezelelweyo zeklinikhi besebenzisa i-adjuvant PBMT kunyango lwe-COVID-19 pneumonia.”
Kwi-PBMT, ukukhanya kukhanyiswa zizicubu ezonakeleyo kwaye amandla okukhanya afunxwa ziiseli, nto leyo eqala uthotho lweempendulo zeemolekyuli eziphucula ukusebenza kweeseli kwaye zikhawulezise inkqubo yokuphiliswa komzimba. I-PBMT ibonakalise iimpawu zokulwa nokuvuvukala kwaye ivela njengendlela eyahlukileyo yokuphelisa iintlungu, unyango lwe-lymphedema, ukuphiliswa kwamanxeba kunye nokwenzakala kwemisipha. Ukusetyenziswa kwe-PBMT yokugcina unyango lwe-COVID-19 kusekelwe kwingcamango yokuba ukukhanya kwe-laser kufikelela kwizicubu zemiphunga ukunciphisa ukudumba nokukhuthaza ukuphiliswa. Ukongeza, i-PBMT ayingenisi ntsholongwane, ixabisa kancinci, kwaye ayinazo iziphumo ebezingalindelekanga ezaziwayo.
I-laser ye-MLS isebenzisa iskena esiphathwayo esinee-diode ezimbini ze-laser ezivumelanisiweyo, enye i-pulsed (ekwaziyo ukuhlengahlengiswa ukusuka kwi-1 ukuya kwi-2000 Hz) ekhupha kwi-905 nm kwaye enye i-pulsed kwi-808 nm. Zombini ii-wavelengths ze-laser zisebenza ngaxeshanye kwaye ziyahambelana. I-laser ibekwe kwi-20 cm ngaphezulu kwesigulana esileleyo, ngaphesheya kwentsimi yemiphunga. Ii-laser azinantlungu kwaye izigulana zihlala zingazi ukuba unyango lwe-laser luyenzeka. Le laser idla ngokusetyenziswa kwizicubu ezinzulu ezifana namalungu esinqe kunye ne-pelvic, ajikelezwe zimisipha ezityebileyo. Umthamo wonyango osetyenziselwe ukufezekisa iinjongo ezinzulu ze-pelvic yayiyi-4.5 J/cm2. Umbhali-mbhali wophando uGqr. Soheila Mokmeli ubalele ukuba i-7.2 J/cm2 isetyenzisiwe eluswini, inika umthamo wonyango wamandla e-laser ongaphezulu nje kwe-0.01 J/cm2 emiphungeni. Le dosi iyakwazi ukungena eludongeni lwesifuba kwaye ifikelele kwizicubu zemiphunga, ivelise isiphumo sokulwa nokuvuvukala esinokuthintela ngokwethiyori iziphumo zesiphepho se-cytokine kwi-pneumonia ye-COVID-19. Ukuze ufumane ulwazi oluthe kratya malunga nonyango lwe-laser lwe-MLS, nceda uthumele i-imeyile kuMark Mollenkopf [email protected] okanye utsalele umnxeba ku-800-889-4184 ulwandiso 102.
Ukuze ufumane ulwazi oluthe kratya malunga nalo msebenzi wokuqala kunye nenkqubo yophando, nceda unxibelelane noScott A. Sigman, MD ku-[email protected] okanye utsalele umnxeba ku-978-856-7676.
1 Sigman SA, Mokmeli S., Monich M., Vetrichi MA (2020). Indoda eneminyaka engama-57 ubudala yase-Afrika-Amerika ene-pneumonia enzima ye-COVID-19 isabela kunyango oluxhasayo lwe-photobiomodulation (PBMT): ukusetyenziswa kokuqala kwe-PBMT kwi-COVID-19. Am J Case Rep 2020; 21:e926779. DOI: 10.12659/AJCR.926779