U-Endre Mester, ugqirha waseHungary, kunye nogqirha wotyando, unikwe inkokhelo yokufumanisa iziphumo zebhayoloji ze-laser zamandla aphantsi, okwenzeka kwiminyaka embalwa emva kokuveliswa kwe-ruby laser ngo-1960 kunye nokuveliswa kwe-helium-neon (HeNe) ngo-1961.
UMester waseka iLaser Research Centre kwiYunivesithi Yezonyango iSemmelweis eBudapest ngo-1974 waza waqhubeka esebenza apho ubomi bakhe bonke. Abantwana bakhe baqhubeka nomsebenzi wakhe baza bawuthumela eUnited States.
Ngo-1987 iinkampani ezithengisa iilaser zabanga ukuba ziyakwazi ukunyanga iintlungu, ukukhawulezisa ukuphiliswa kokwenzakala kwezemidlalo, kunye nokunye, kodwa bekukho ubungqina obuncinane boku ngelo xesha.
U-Mester ekuqaleni wayibiza le ndlela ngokuthi "i-laser biostimulation", kodwa kungekudala yabizwa ngokuba "yinqanaba eliphantsi lonyango lwe-laser" okanye "unyango lwesibane esibomvu". Ngee-diode ezikhupha ukukhanya ezilungiselelwe abo bafunda le ndlela, emva koko yaziwa ngokuba "yinqanaba eliphantsi lonyango lokukhanya", kunye nokusombulula ukudideka malunga nentsingiselo echanekileyo "yenqanaba eliphantsi", igama elithi "photobiomodulation" lavela.