I-Gout kunye ne-Hyperuricemia
Ihlobo elishushu, i-braai yokutya kwaselwandle, iziselo ezibandayo ezibandayo, umoya opholileyo ovuthuzayo …… asingomgangatho wakho wobomi, kodwa ixesha elide, lumka i-uric acid iphezulu kakhulu, nto leyo ebangela ukuhlaselwa yi-gout!
UGu Bingjie, usekela-gqirha oyintloko kwicandelo le-rheumatology kunye ne-immunology kwiSibhedlele sokuQala saseNanjing, uthe kwiintsuku ezimbalwa ezidlulileyo, phantse izigulane ezingama-20 ezine-hyperuricemia kunye ne-gout zibonwa yonke imihla, ama-90% azo ngamadoda, kwaye ubudala bokuqala buqala buncinci.
Ngoko ke, i-gout yenzeka njani kwaye kutheni ixhaphake kakhulu kumadoda?
I-Gout inxulumene namanqanaba e-uric acid egazini
I-Gout, isifo sokudumba esibangelwa kukubekwa kweekristale ze-urate emalungeni ngenxa yamanqanaba aphezulu e-uric acid, kunye ne-hyperuricemia kunye ne-gout ziimeko ezahlukeneyo zesifo esinye.
Kwiimeko eziqhelekileyo, i-90% ye-uric acid iya kutsalwa ngumzimba, kwaye i-10% eseleyo iya kukhutshwa emzimbeni ngendlela yomchamo, ukubila, kunye nendle ukuze inqanaba le-uric acid yomzimba ligcine ibhalansi eguquguqukayo. Nangona kunjalo, xa ii-purines ezininzi zityiwa zingene kwimveliso engaphezulu kwe-uric acid, okanye i-uric acid metabolism ayinakukhutshwa, ibhalansi iya kwaphuka, nto leyo ekhokelela ekugcinweni kwe-uric acid egazini, kwaye ngokuhamba kwegazi kuzo zonke iindawo zomzimba, kumalungu ngokuhamba kwegazi okucothayo, ubushushu obuphantsi buya kufakwa ukuze kwenziwe iikristale ze-urate, nto leyo ekhokelela kwimpendulo yokuvuvukala, ebangela intlungu enzima.
Kwiimeko eziqhelekileyo, i-90% ye-uric acid iya kutsalwa ngumzimba, kwaye i-10% eseleyo iya kukhutshwa emzimbeni ngendlela yomchamo, ukubila, kunye nendle ukuze inqanaba le-uric acid yomzimba ligcine ibhalansi eguquguqukayo. Nangona kunjalo, xa ii-purines ezininzi zityiwa zingene kwimveliso engaphezulu kwe-uric acid, okanye i-uric acid metabolism ayinakukhutshwa, ibhalansi iya kwaphuka, nto leyo ebangela ukugcinwa kwe-uric acid egazini, kwaye ngokuhamba kwegazi kuzo zonke iindawo zomzimba, kumalungu ngokuhamba kwegazi okucothayo, ubushushu obuphantsi, kuya kufakwa ukwenza iikristale ze-urate, nto leyo ebangela ukuvuvukala, okubangela intlungu enzima.
Kutheni i-gout “inceda” amadoda ngakumbi?
Ukongeza, uphando lubonise ukuba iihomoni, njengezilawuli ezibalulekileyo zemetabolism, zidlala indima ekuvelisweni nasekukhutshweni kwe-uric acid, kuquka iihomoni zesini, ihomoni ye-adrenocorticotropic, ihomoni ye-thyroid, i-insulin, njalo njalo. Xa inkqubo ye-endocrine ingasebenzi kakuhle, ukukhutshwa okanye ukusebenza kwezi homoni kunokuchaphazeleka, okukhokelela ekwandeni kwamanqanaba e-uric acid, nto leyo ebangela uphuhliso lwe-gout.
Kukwakho nomahluko wendalo kwizinga leehomoni phakathi kwamadoda nabafazi, apho ii-androgens ziphezulu kumadoda kunye nee-estrogens kubasetyhini. I-estrogen inokukhuthaza ukukhutshwa kwe-uric acid kwaye ithintele ukwakheka kwe-urate. Kwelinye icala, ii-Androgens zithintela ukukhutshwa kwe-uric acid kwizintso kwaye zinciphise ukusebenza kakuhle kwe-metabolism yezintso, nto leyo ekhokelela kumanqanaba aphezulu e-uric acid emzimbeni, ngaloo ndlela ikhawulezisa ukwakheka kunye nokufakwa kweekristale ze-uric acid. Idatha ibonisa ukuba kuluntu ngokubanzi, ngaphezulu kwe-95% ye-gout yenzeka kumadoda, ukwenzeka kwabasetyhini kungaphantsi kwe-5%, kwaye umlinganiselo wamadoda kubafazi usondele kwi-20:1.
Ndingawunciphisa njani umngcipheko wokuba ne-gout?
Akuphelelanga apho, ukubakho kwe-gout okanye i-hyperuricemia kukwanxulumene kakhulu nokutya okungenampilo kunye nemikhwa yokuphila. Ke ngoko, ukunciphisa umngcipheko we-gout, ungayithintela yonke imihla ngokwenza oku kulandelayo:
- Lawula umlomo wakho: Kuphephe ukutya ukutya okune-purine eninzi, ungatya ukutya okune-alkaline eninzi ukuphucula ukunyibilika kwe-uric acid kumchamo kunye nokwandisa ubungakanani be-uric acid ephumayo.
- Sela amanzi angakumbi: Ehlotyeni, umzimba womntu ubila kakhulu, kwaye ukuba akuncedi ngexesha elifanelekileyo, oko kukhokelela kuxinzelelo lwegazi, kwaye uxinzelelo lwe-uric acid egazini nalo luyanda ngokufanelekileyo, nto leyo ebangela i-gout.
- Ukulawula Ubunzima: Ukutyeba kakhulu akusiyosifo se-metabolic kuphela, kodwa kukwangumngcipheko ozimeleyo wokukhula kwe-hyperuricemia kunye ne-gout kuba iiseli zamafutha zikhupha ii-purines ezininzi, ezonyusa amanqanaba e-uric acid.
- Shukumisa imilenze yakho: Izifundo zamanye amazwe zibonise ukuba ukwenza umthambo we-aerobic ophantsi (njengokuhamba ngokukhawuleza, ukubaleka, ukudada, njl.njl.) imizuzu engama-30 ukuya kwengama-60, izihlandlo ezi-4 ukuya kwezi-5 ngeveki, kunokunciphisa ukwanda kwe-gout.
Uphononongo lubonisa ukuba ukukhanya okubomvu kunokunciphisa iimpawu ze-gout
Ukongeza ekugcineni indlela yokuphila esempilweni, kwinkqubo yezonyango yokunyanga i-gout, amalungu avuvukileyo, kunye nentlungu ziba yingxaki ephambili yesigulana esikhathazayo, kukho iincwadi ezininzi zesayensi ezibonisa ukuba izigulana ze-gout ezisebenzisa unyango lokukhanya okubomvu zinokuphucula imetabolism yezicubu, zikhawulezise ukubuyiselwa kwemithambo-luvo eyonakeleyo, kwaye zinciphise ngokufanelekileyo ixesha lokudumba kunye nentlungu ukunciphisa intlungu yomzimba neyengqondo yesigulana, kunye nokukhuthaza inkqubo yokuchacha, kwaye kuphononongo lwakutshanje lweklinikhi lubonise ukuba i-88% yezigulana ezine-gout emva konyango lokukhanya okubomvu iintlungu ziye zaphucuka kakhulu, kwaye zafikelela kwisiphumo sokuphelisa iintlungu ngokupheleleyo. Kuphononongo lwakutshanje lweklinikhi, kuboniswe ukuba i-88% yezigulana ze-gout ziye zaphucuka kakhulu kwiintlungu emva konyango lokukhanya okubomvu, kwaye zafikelela kwisiphumo sokuphelisa iintlungu ngokupheleleyo.
Ukuqinisekiswa okuninzi kwezonyango kukwabonise ukuba ukukhanya okubomvu kunokufunxwa ngumzimba kwaye ukungena ngamandla, kunokukhuthaza ukukhula kwe-axons yemithambo-luvo eyonakeleyo, ukuze ukwakheka kwe-nerve myelin sheaths kukhawulezise ukulungiswa kunye nokuvuselelwa kwemithambo-luvo eyonakeleyo, kwangaxeshanye, ukukhanya okubomvu kunokwenza izicubu zasekuhlaleni zomxholo we-pentazocine zinciphe, kwaye ngaloo ndlela zidlale indima ye-analgesia, enceda ekunciphiseni iintlungu.
I-MERICAN Health Cabin esekelwe kunyango lokukhanya okubomvu idibanisa uluhlu olubanzi lwee-wavelengths zokukhanya ukuvelisa iziphumo zebhayoloji kulusu lomzimba wonke, ezinokuphucula imetabolism yezicubu kunye nesimo sesondlo, zonyuse i-phagocytosis kunye nokungena kwemithambo yegazi, kwaye zithintele ngokufanelekileyo ukubonakaliswa kwee-cytokines ezinxulumene nentlungu, ezinceda ekufunxeni ii-exudates ezivuthayo, zinciphise iintlungu zamalungu esigulana, zinciphise i-index ye-uric acid yegazi, kwaye zikhuthaze ukuphuculwa kweempawu zeklinikhi kunye nokuvuselelwa kwamalungu.
Kule mihla, i-gout ibe "yesine ephezulu" emva kwesifo seswekile, uxinzelelo lwegazi oluphezulu kunye ne-hyperlipidemia. Ngokusekelwe kwindlela yokuphila yesayensi nesempilweni, eyongezwa lunyango lokukhanya okubomvu, inokukwazi ukunciphisa iimpawu ezingathandekiyo kwaye ngaloo ndlela ikhuthaze ngempumelelo inkqubo yokuchacha.