Elinye lamalungu angaziwayo emzimbeni ukubaunyango olululaizifundo ziye zavavanya izihlunu.Izicubu zomzimba zomntu zineenkqubo ezikhethekileyo zokuvelisa amandla, ezifuna ukukwazi ukunika amandla kuzo zombini ixesha elide lokusetyenziswa okuphantsi kunye nexesha elifutshane lokusetyenziswa ngamandla.Uphando kule ndawo luye lwakhawuleza kakhulu kule minyaka imbalwa idlulileyo, kunye nenani lezifundo ezitsha ezikumgangatho ophezulu rhoqo ngenyanga.Ukukhanya okubomvu kunye ne-infrared kuye kwafundwa ngokunzulu kwiintlobo zezifo kunye neemeko, ukusuka kwintlungu edibeneyo ukuya ekuphulukiseni amanxeba, mhlawumbi ngenxa yokuba iziphumo zeselula zichazwe ukuba zisebenze kwinqanaba elisisiseko lamandla.Ke ukuba ukukhanya kungena ezantsi kwizicubu zezihlunu, ngaba kunokwenza iziphumo eziluncedo apho?Kweli nqaku siza kuphonononga ukuba ukukhanya kusebenzisana njani nezi nkqubo kwaye zeziphi iingenelo ezinokuzisa, ukuba zikhona.
Ukukhanya kunokunxibelelana nokusebenza kwezihlunu, kodwa njani?
Ukuqonda ukuba ukukhanya kunokuchaphazela njani izicubu zomzimba, kufuneka siqale siqonde ukuba izicubu zomzimba zisebenza njani.Amandla ayimfuneko kubomi kwiseli nganye yazo zonke iintlobo esizaziyo ngoku.Le nyaniso yobomi ibonakala ngokucacileyo kwizicubu zezihlunu, ukusuka kumbono womatshini, kunalo naluphi na uhlobo lwezicubu.Ekubeni izihlunu zibandakanyeka kwintshukumo, kufuneka zibe zivelisa kwaye zisebenzise amandla, okanye aziyi kuhamba.Nantoni na enceda ngale mveliso yamandla isisiseko iya kuba luncedo.
Indlela yonyango yokukhanya
Unyango olukhanyayo lunendlela eyaziwayo kuyo nayiphi na iseli yomzimba ene-mitochondrion (i-mitochondria yi-organelles enoxanduva lokuvelisa amandla).Ungajonga kwiCytochrome C Oxidase kunye neNitric Oxide ukuze ufunde ngakumbi ngezinto ezithile apha, kodwa ngokusisiseko ingqikelelo kukuba zombini ukukhanya okubomvu kunye nokufutshane kwe-infrared kunceda i-mitochondria yethu ukugqiba inkqubo yokuphefumla, ukunika ngakumbi i-CO2 kunye ne-ATP (amandla).Oku ngokwethiyori kuya kusebenza kuyo nayiphi na iseli yomzimba, ngaphandle kwezo ziswele imitochondria ezifana neeseli ezibomvu zegazi.
Uqhagamshelwano lwemisipha-amandla
Enye yeempawu eziphambili zeeseli zezihlunu kukuba zininzi kakhulu kwi-mitochondria, zifuna ukuba zizalisekise iimfuno eziphezulu zamandla.Oku kusebenza kwizihlunu zamathambo, izihlunu zentliziyo, kunye nezihlunu ezigudileyo zezihlunu njengoko unokuzifumana kumalungu angaphakathi.Ubuninzi be-mitochondria kwizicubu zomzimba ziyahluka phakathi kweentlobo kunye namalungu omzimba, kodwa zonke zidinga iqondo eliphezulu lamandla ukuze zisebenze.Ubukho obutyebileyo ngokubanzi bucebisa ukuba kutheni abaphandi bonyango olukhanyayo banomdla kwisicelo sokujolisa izihlunu, ngakumbi kunezinye izicubu.
Iiseli ze-Muscle stem - ukukhula kunye nokulungiswa okuphuculwe kukukhanya?
Iiseli ze-Myosatellite, uhlobo lwe-muscle stem cell ebandakanyekayo ekukhuleni nasekulungiseni, nayo ingundoqo ekujoliswe kuyo yonyango olukhanyayo1,5, mhlawumbi kunye neyona njongo iphambili enika imiphumo yexesha elide.Ezi seli zesathelayithi zisebenza ngokuphendula ubunzima (njengokusuka kwintshukumo yomatshini njengokuzilolonga okanye ekwenzakaleni) - inkqubo enokuthi iphuculwe ngonyango olulula9.Njengeeseli ze-stem kuyo nayiphi na indawo yomzimba, ezi seli zesathelayithi ziphambili kwiiseli zemisipha eziqhelekileyo.Ngokuqhelekileyo zikhona kwindawo ekhululekileyo, engasebenziyo, kodwa iya kuguqukela kwezinye iiseli ze-stem okanye iguqule iiseli ze-muscle ezisebenza ngokupheleleyo njengenxalenye yenkqubo yokuphulukisa, ekuphenduleni ukulimala okanye ukuxhatshazwa.Uphando lwakutsha nje lukhomba kwimveliso yamandla e-mitochondrial ngaphakathi kweeseli ze-stem njengoyena mlawuli uphambili we-fate6, eyona nto imisela 'inkqubo' yabo kunye nesantya kunye nokusebenza kwabo kakuhle.Kuba ingqikelelo emva konyango lokukhanya kukuba inokuba ngumkhuthazi onamandla wokusebenza kwe-mitochondrial, kukho indlela ecacileyo yokuchaza ukuba ukukhanya kunokuphucula njani ukukhula kwezihlunu zethu kunye nokulungiswa ngeeseli ze-stem.
Ukudumba
Ukuvuvukala yinto eqhelekileyo ehambelana nokulimala kwemisipha okanye uxinzelelo.Abanye abaphandi bacinga ukuba ukukhanya kunokunceda (ukuba kusetyenziswe ngokufanelekileyo) ukunciphisa ubunzima be-inflammation3 (ngokwandisa amanqanaba e-CO2 - eqhubeka nokuthintela i-cytokines / i-prostaglandins evuthayo), ngaloo ndlela ivumela ukulungiswa okusebenzayo ngaphandle kwe-scarring / fibrosis.
Ixesha lokuposa: Sep-21-2022